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Variability in human drug response

The fact that each patient reacts differently to one given treatment is both an obstacle and a challenge for pharmacology. The eighth international symposium organized by the Esteve Foundation included several aspects related to the diversity of responses to drugs. Geoffrey T. Tucker, from the Department of Molecular Pharmacology and Pharmacogenetics of the University of…

1999

Pharmacokinetics: Development of an exquisitely practical science

Around 30 articles which contributed in an exceptional manner to the huge progress of pharmacokinetics are included in the second volume of Pharmacotherapy Revisited: an Esteve Foundation Series, under the title Pharmacokinetics: development of an exquisitely practical science. This time, the most relevant articles were selected by Patrick du Souich, from the Department of Pharmacology…

1999

Glosario de investigaci贸n cl铆nica y epidemiol贸gica

This monograph compiles more than 700 entries that offer a wide spectrum of concepts 鈥搑anging from pharmacology and statistics to ethics and epidemiology鈥 in an attempt to provide a dictionary of research methodology to Research Committee and Clinical Research Ethics Committee members of very different origin, as well as to any healthcare provider with an…

1998

Problemas y controversias en torno al ensayo cl铆nico

Clinical trials have become paradigms of the scientific method applied in the clinical field. Accordingly, this monograph number 22 raises some of the most problematic and controversial aspects regarding a method which, over the years, has increased its importance in present medicine. This method has added sophistication with the enforcement of聽Good Clinical Practice Regulations聽or聽Standard Operating…

1998

Medicina y medios de comunicaci贸n. Traducci贸n al espa帽ol de una serie publicada en ‘The Lancet’

Medicine and the Media聽gathers a series of articles published in聽The Lancet聽about the conflicts that arise when the two disciplines 鈥搒cience and journalism鈥 converge and lead to sometimes difficult and unsatisfactory relationships. The aspects analyzed were: news value, sources and the issue of scientific fraud, the influence and power of the media, how medical TV programs…

1997

Traducci贸n y lenguaje en medicina

The richness of the medical language is too often disturbed by scientific writing and translation. Dr. Fernando Navarro, a trained clinical pharmacologist, has wide experience in the difficult task of translation. The monograph Translation and Language in Medicine gathers some of the articles published by Dr. Navarro in Medicina Cl铆nica, which relate to linguistic conflicts that often impair…

1997

The clinical pharmacology of sport and exercise

As antidoping controls have gained wide repercussion in the media on account of their performance in great contests, much talk has ensued regarding the misuse of drugs in sports. However, there is little discussion about the true effect of medicinal products on physical performance or about whether evidence of all possible drug-related effects on exercise…

1997